Abstract

Mini Review

Exploring the Potential of Medicinal Plants in Bone Marrow Regeneration and Hematopoietic Stem Cell Therapy

Ugwu Okechukwu Paul-Chima* and Alum Esther Ugo

Published: 31 January, 2025 | Volume 8 - Issue 1 | Pages: 001-005

Blood cell production through hematopoiesis within the bone marrow serves both to maintain blood equilibrium and to respond to tissue injury and infectious demands. Hematopoietic stem cell (HSC) therapy developments have revolutionized medical treatment approaches for anemia leukemia and bone marrow failure caused by chemotherapy or radiation exposure. The therapeutic compounds present in medicinal plants have traditionally supported blood health and researchers now understand these plants could help regenerate bone marrow tissue. The analysis investigates how phytochemicals affect HSC proliferation and differentiation while supporting HSC survival. The medicinal plants Panax ginseng, Astragalus membranaceus, and Curcuma longa receive special attention for their documented ability to enhance hematopoiesis in preclinical and clinical settings. This review examines the challenges that include standardization issues, toxicity concerns, and regulatory barriers alongside future perspectives about combining plant-based therapies with traditional treatments to improve bone marrow recovery and health results. 

Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001019 Cite this Article Read Full Article PDF

Keywords:

Hematopoiesis; Hematopoietic stem cells; Bone marrow regeneration; Medicinal plants; Phytochemicals; Panax ginseng; Astragalus membranaceus; Curcuma longa; Bioactive compounds; Chemotherapy-induced myelosuppression

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