Published: 15 April, 2019 | Volume 2 - Issue 1 | Pages: 018-026
Figure 3:
Bone marrow biopsy showing increased cellularity (70%) due to increased erythropoiesis and megakaryocytic (EM) proliferation with loos clusters of large megakaryocytes with hyper-lobulated nuclei in WHO defined JAK2V617F ET (a) in two studies of Piche 2008 and 2018. Dense clusters of large to giant megakaryocytes with hyperchromatic hypo/hyper-lobulated bulbous (cloudy) nuclei and relative reduction of erythropoiesis in WHO defined CALR mutated ET in the study of Pich 2018. Bone marrow biopsy with fields of normocellular and reduced cellularity (h) and the presence of dense clustered large to giant megakaryocytes with hyper-lobulated staghorn-like nuclei (i and j) in WHO defined MPL515 mutated ET in the study of Pich 2018.
Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001003 Cite this Article Read Full Article PDF
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